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If you are purchasing medications on this site, it is important to be aware of potential drug interactions. This report displays the potential drug interactions for codeine and Endep (amitriptyline).
Interactions between your drugs
Using codeine together with amitriptyline can increase the risk of a rare but serious condition called the serotonin syndrome. Symptoms may include confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. If you experience any of these symptoms during treatment, you should contact your doctor immediately. Combining these medications may also increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. It is important to avoid or limit the use of alcohol while being treated with these medications and to avoid driving or operating hazardous machinery until you know how the medications affect you. Tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
If you have any concerns about potential drug interactions or other medication-related issues, always consult your healthcare provider.
Drug Interaction Classification
These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Further information: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer: The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition.