Interactions  for Codeine and Delsym

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Potential Drug Interactions for Codeine and Delsym (dextromethorphan)

If you are planning to purchase medications on this site, it is important to be aware of potential drug interactions. Using codeine and dextromethorphan together can increase the risk of a rare but serious condition called the serotonin syndrome. Symptoms may include confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death.

It is important to contact your doctor immediately if you experience any of these symptoms during treatment. Combining these medications may also increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. It is important to avoid or limit the use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you.

Make sure to inform your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and Food Interactions

Consumer information for this interaction is not currently available. However, it is generally advised to avoid or limit consumption of alcohol while being treated with CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills. Patients receiving CNS-active agents should be warned of this interaction and advised to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them. Notify your physician if you experience excessive or prolonged CNS effects that interfere with your normal activities.

Therapeutic Duplication Warnings

No warnings were found for your selected drugs. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.

– Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.

– Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

– Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

– Unknown: No interaction information available.

Further Information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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