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Interactions between your drugs
This report displays the potential drug interactions for the following 2 drugs:
– Codeine
– Plaquenil (hydroxychloroquine)
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Drug Interaction Classification
These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
– Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
– Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
– Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
– Unknown: No interaction information available.
Interactions between your drugs
Hydroxychloroquine may reduce the effectiveness of codeine. You may need a dose adjustment if you have been taking codeine and are starting treatment with hydroxychloroquine. Let your doctor know if your condition changes or you experience reduced or inadequate relief of your symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
You may want to limit your consumption of grapefruit or grapefruit juice during treatment with hydroxychloroquine. Grapefruit juice can significantly increase the blood levels and effects of hydroxychloroquine, which may result in an irregular heart rate or other conduction disturbances. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with hydroxychloroquine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.