Cheap No Prescription Blog: Comparison of Alternatives to Codeine, Pseudoephedrine, and Pyrilamine

No RX Needed

This medication, containing codeine, pseudoephedrine, and pyrilamine, is prescribed for various symptoms such as allergies, cold symptoms, cough, cough and nasal congestion, nasal congestion, rhinorrhea, and sinus symptoms. It may also be used for other purposes not listed here.


Hydroxyzine is used to relieve anxiety or itching. However, it causes sedation and can affect a person’s ability to drive or operate machinery. It should not be used during pregnancy or while…

Prescription and OTC

Loratadine is an antihistamine that effectively treats allergic reactions such as hay fever. It is unlikely to cause drowsiness and is prescribed for allergic rhinitis, urticaria, and allergic…

Learn more about Hydroxyzine and Loratadine.

Generic Status

No lower-cost generic available for this medication.

Ratings & Reviews

Be the first to share your experience with this drug. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1318 ratings on 45% of reviewers reported a positive effect, while 37% reported a negative effect. Loratadine has an average rating of 4.8 out of 10 from a total of 131 ratings on 37% of reviewers reported a positive effect, while 54% reported a negative effect.

Side Effects

See also: codeine / pseudoephedrine / pyrilamine side effects in more detail. See also: hydroxyzine side effects in more detail. See also: loratadine side effects in more detail.

Pricing and Coupons

Prices are without insurance. We could not find an exact match for this medicine. Try searching the Price Guide directly.

View all hydroxyzine prices. View all loratadine prices.

Dosage Form(s) Available

Intramuscular solution, oral capsule, oral syrup, oral tablet, oral tablet, chewable, oral tablet, disintegrating.

Brand Names

Vistaril, Alavert, Allergy Relief 24 Hour, Allergy Relief Tablets, Bactimicina Allergy, Children’s Allergy Relief 24 Hour, Children’s Claritin Allergy, Claritin, Claritin 24 Hour Allergy, Claritin Reditabs, Clear-Atadine Children’s, Help I Have Allergies, Loratadine Reditab, ohm Allergy Relief, Tavist ND, Wal-itin.

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. Hydroxyzine has a half-life of 16 hours. Loratadine has a half-life of 7 hours.

CSA Schedule **

Codeine / pseudoephedrine / pyrilamine has a low potential for abuse relative to those in schedule 4. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. Hydroxyzine and loratadine are not subject to the Controlled Substances Act.

Pregnancy Category

See the full pregnancy warnings document for each medication.

Drug Interactions

A total of 633 drugs are known to interact with codeine / pseudoephedrine / pyrilamine. A total of 557 drugs are known to interact with hydroxyzine. A total of 93 drugs are known to interact with loratadine.

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of pyrilamine and hydroxyzine such as dizziness and drowsiness. No known alcohol/food interactions exist for loratadine, but always consult your healthcare provider.

Disease Interactions

No disease interactions were found for these medications.

First Approval Date

N/A for codeine / pseudoephedrine / pyrilamine. Hydroxyzine was approved on April 12, 1956, and loratadine was

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