Buy online: Comparison of Alternatives to Guiatussin with Codeine

No RX Needed: Guiatussin with Codeine

Guiatussin with Codeine is prescribed for cough relief, but may also have other uses not listed in this medication guide.

No RX Needed: Benzonatate

Benzonatate is used to relieve dry cough, but it is important to swallow the capsules whole to avoid the risk of fatal overdosage if opened. It is prescribed for cough relief.

Prescription and OTC: Mucinex

Mucinex is an expectorant that helps thin mucus, making it easier to clear through coughing. It may also be used off-label to increase fertility in women with hostile mucus as the cause of infertility.

Learn more about codeine/guaifenesin, benzonatate, and Mucinex.

Generic Status

Lower-cost generic options are available for all three medications.

Ratings & Reviews

No reviews are available for Guiatussin with Codeine. Benzonatate has an average rating of 3.8 out of 10 from 728 ratings, with 28% of reviewers reporting a positive effect and 64% reporting a negative effect. Mucinex has an average rating of 6.2 out of 10 from 149 ratings, with 55% of reviewers reporting a positive effect and 34% reporting a negative effect.

Drug Class

All three medications belong to different drug classes.

Side Effects

See detailed information on side effects for Guiatussin with Codeine, benzonatate, and Mucinex.

Pricing and Coupons

Prices for benzonatate and Mucinex are available, but no exact match was found for Guiatussin with Codeine. Check the Price Guide for more information.

Dosage Form(s) Available

Both benzonatate and Mucinex are available in oral capsule or tablet form.

Brand Names

Guiatussin with Codeine has several brand names, including Cheratussin AC and Virtussin A/C. Other brands of guaifenesin include Robitussin Mucus + Chest Congestion and Mucinex Maximum Strength. Benzonatate is also sold under the brand name Tessalon.

Half Life

The half-life of Guiatussin with Codeine is 3.5 hours, while benzonatate has no reported half-life. Mucinex has a half-life of 1 hour.

CSA Schedule

Guiatussin with Codeine is subject to multiple schedules, while benzonatate and Mucinex are not subject to the Controlled Substances Act.

Pregnancy Category

See full pregnancy warnings for Guiatussin with Codeine, benzonatate, and Mucinex.

Drug Interactions

Guiatussin with Codeine has 472 known drug interactions, while benzonatate has 1 moderate drug interaction. Mucinex has no known drug interactions, but always consult with a healthcare provider as interactions may still exist.

Alcohol/Food/Lifestyle Interactions

Guiatussin with Codeine should not be used with alcohol or medications that contain alcohol. No known alcohol/food interactions exist for benzonatate or Mucinex, but always consult with a healthcare provider.

Disease Interactions

No known disease interactions exist for any of the three medications, but always consult with a healthcare provider.

First Approval Date

Approval dates vary for each medication.

WADA Class

No WADA classifications are available for any of the three medications.

More Information

No patient or professional resources are available for any of the three medications.

Learn more about cough relief and other related treatments.

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