Drugs A to Z
Potential Drug Interactions: Codeine and Sumatriptan
This report highlights the possible interactions between codeine and sumatriptan. Combining these drugs can increase the risk of serotonin syndrome, a rare but serious condition that can cause confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may lead to coma and even death. If you experience any of these symptoms during treatment, contact your doctor immediately. Additionally, using these medications together may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Avoid or limit alcohol use while taking these drugs and refrain from driving or operating hazardous machinery until you know how they affect you. Inform your doctor of all medications you use, including vitamins and herbs. Do not stop taking any medication without consulting your doctor.
Drug and Food Interactions
No alcohol or food interactions were found. However, it is important to consult your healthcare provider as this does not necessarily mean that no interactions exist.
Therapeutic Duplication Warnings
No warnings were found for the selected drugs. Therapeutic duplication warnings are only given when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
The following classifications are only a guideline. It is difficult to determine the relevance of a particular drug interaction to a specific individual. Always consult your healthcare provider before starting or stopping any medication.
- Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
- Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
- Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
- Unknown: No interaction information available.
Further Information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer: This article is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition.