Interactions of Codeine, Guaifenesin, and Phenylpropanolamine


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Drug Interactions with Codeine Syrup

Codeine Syrup is a powerful medication that can interact with other drugs. There are 585 known drugs that can interact with codeine/guaifenesin/phenylpropanolamine, along with 22 disease interactions and 1 alcohol/food interaction. Of these interactions, 153 are major, 428 are moderate, and 4 are minor.

If you are taking other medications, it is important to check for potential interactions. You can enter your other medications to view a detailed report of any potential interactions.

Most Frequently Checked Interactions

You can view interaction reports for codeine/guaifenesin/phenylpropanolamine and the medicines listed below:

  • Major
  • Moderate
  • Minor
  • Unknown

Codeine Syrup Alcohol/Food Interactions

There is 1 alcohol/food interaction with codeine/guaifenesin/phenylpropanolamine.

Codeine Syrup Disease Interactions

There are 22 disease interactions with codeine/guaifenesin/phenylpropanolamine, which include:

Drug Interaction Classification

It is important to note that these classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.

  • Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
  • Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
  • Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
  • Unknown: No interaction information available.

Further Information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer: This article is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition.

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