Comparison of Codeine and Gabapentin

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Prescription Only

Codeine is a pain-reliever that can be addictive and may cause constipation. Its effectiveness can vary between individuals, so it should only be used for pain relief. View more

Gabapentin may be used to treat seizures and nerve pain, but it can cause dizziness or drowsiness. Gabapentin enacarbil (Horizant) is a prodrug of gabapentin. View more

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Generic Status

Lower-cost generic versions are available for both drugs.

Ratings & Reviews

Codeine has an average rating of 7.8 out of 10 from 60 ratings on 69% of reviewers reported a positive effect, while 15% reported a negative effect.

Gabapentin has an average rating of 7.1 out of 10 from 2441 ratings on 63% of reviewers reported a positive effect, while 22% reported a negative effect.

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Drug Class

Both drugs belong to different classes.

Side Effects

Common side effects for codeine include ataxia, dizziness, drowsiness, fatigue, fever, nystagmus disorder, sedated state, and viral infection. Common side effects for gabapentin include dizziness and drowsiness. View more

Pricing and Coupons

Prices for both drugs vary depending on quantity and dosage. View all prices

Dosage Form(s) Available

Both drugs are available in different forms.

Brand Names

Gabapentin has several brand names, including Fanatrex, Gabarone, Gralise, and Neurontin. Codeine does not have a brand name.

Half Life

The half-life of codeine is 3.5 hours, while the half-life of gabapentin is 6 hours.

CSA Schedule

Codeine is a controlled substance with a high potential for abuse, while gabapentin is not subject to the Controlled Substances Act.

Pregnancy Category

Both drugs have warnings for use during pregnancy. View full warnings

Drug Interactions

Both drugs have known interactions with other medications. View all interactions

Alcohol/Food/Lifestyle Interactions

Both drugs have interactions with alcohol and certain foods or lifestyles. View all interactions

Disease Interactions

There are no known disease interactions for either drug.

First Approval Date

Codeine was first approved on July 16, 2009, while gabapentin was first approved on December 30, 1993.

WADA Class

Neither drug is classified by the World Anti-Doping Agency.

More Information

Find more resources and treatment guides for both drugs. View more

The information provided on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Always consult your healthcare provider before taking any medication.

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