Comparison between Codeine and Hydrocodone

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Prescription Only

Codeine is a pain-reliever that can be addictive and cause constipation. Its effectiveness varies between individuals, so it should only be used for pain relief when prescribed by a doctor.

Hydrocodone is a potent pain-relieving medicine, but its use is limited due to its potential for addiction and dependence. It is one of the most misused opioids in the United States and should only be used as prescribed.

View popular comparisons between medications for pain relief.

Generic Status

Lower-cost generic versions of both codeine and hydrocodone are available.

Ratings & Reviews

Codeine has an average rating of 7.8 out of 10 from 60 ratings on, with 69% of reviewers reporting a positive effect.

Hydrocodone has an average rating of 5.6 out of 10 from 194 ratings on, with 44% of reviewers reporting a positive effect.

View all reviews for codeine and hydrocodone.

Drug Class

Learn about the drug classes that codeine and hydrocodone belong to.

Side Effects

See detailed information about the potential side effects of codeine and hydrocodone.

Pricing and Coupons

Compare prices for codeine and hydrocodone without insurance.

Dosage Form(s) Available

See the different forms in which codeine and hydrocodone are available.

Brand Names

Learn about the brand names of hydrocodone and the generic status of codeine.

Half Life

Find out how long it takes for codeine and hydrocodone to reduce to half their original value.

CSA Schedule **

See the Controlled Substances Act (CSA) schedules for codeine and hydrocodone.

Pregnancy Category

Learn about the pregnancy warnings for codeine and hydrocodone.

Drug Interactions

See the drugs that interact with codeine and hydrocodone.

Alcohol/Food/Lifestyle Interactions

Learn about the interactions between alcohol, food, and medications that contain alcohol and codeine or hydrocodone.

Disease Interactions

See the diseases that interact with codeine and hydrocodone.

First Approval Date

Find out when codeine and hydrocodone were first approved.

WADA Class

See the World Anti-Doping Agency classifications for codeine and hydrocodone.

More Information

Access patient resources, professional resources, and related treatment guides for codeine and hydrocodone.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Medical Disclaimer.

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